Research Awards

At every annual meeting of the International Congress on Nutrition and Integrative Medicine (ICNIM), awards are presented to reports of particularly exceptional research, and to researchers who have made particularly great research achievements.

Awardees up until the present

■ Best Research Award

Year Name Research Title
Year2023 NameChantal Matar (University of Ottawa, Canada) Research TitleLentinula edodes cultured extract consumption during puberty mitigates LPS-induced immune dysfunction in the gut-breast axis and protects against breast cancer in adulthood through epigenetic modulation
Year2022 NameShoichiro Inoue (Otsuka Pharmaceutical Co., Ltd, Japan) Research TitleEffects of foods with function claims containing ETAS® on physical and mental deconditioning caused by shift work
Year2019 NameYin-Ching Chan (Providence University, Taiwan) Research TitleETAS®50 ameliorates cognitive impairment by reducing Aβ via p-Tau pathway, and improving the circadian rhythm signaling
Year2018 NameTominori Kimura (Ritsumeikan University, Japan) Research TitleMolecular mechanisms of actions of AHCCR on human mammary carcinoma cell growth and migration
Year2018 NameJudith A. Smith (UT Health McGovern Medical School, USA) Research TitlePreliminary report on the phase II randomized, double-blind, placebo-controlled evaluation of AHCCR for the eradication of HPV infections in women with HPV positive pap smears
Year2017 NameSuhad M. Bahijri (King Abdulaziz University, Saudi Arabia) Research TitleBeneficial effects of supplementation with Oligonol ? without any dietary or lifestyle modifications ? on cardiometabolic risk factors in a sample of overweight and obese Saudi females
Year2016 NameChantal Matar (University of Ottawa, Canada) Research TitleMicroRNA signature in the chemoprevention of breast cancer byAHCC: Particular role of tumor suppressor miR-335
Year2015 NameHideaki Waki (Teikyo Heisei University, Japan) Research TitleEffect of Enzyme-Treated Asparagus Extract on cerebral blood volume in frontal cortex under psychological stress
Year2014 NameChantal Matar (Faculty of Health Sciences, University of Ottawa, Canada) Research TitleRole of Intestinal Epithelial cells and Toll like receptors in immunomodulatory effects of AHCC
Year2013 NameTatsuya Hisajima (Teikyo Heisei University, Japan) Research TitleEffect of AHCC on the Autonomic Nervous Function
Year2012 NameMehran Haidari (The University of Texas Medical School, USA) Research TitleActive Hexose Correlated Compound (AHCC) Inhibits Disruption of Endothelial Adherens Junction Induced by High Concentration of Glucose
Year2011 NameTakuya Sakurai (Kyorin University, Japan) Research TitlePreventive Effects of Oligonol on Cognitive Impairment in Senescence-accelerated Mice and Identification of its Molecular Target in Hippocampus
Year2010 NameAnuchit Chutaputthi (Phramongkutklao Hospital, Thailand) Research TitleA Study of the Efficacy of Active Hexose Correlated Compound (AHCC) in the Treatment of Chronic Hepatitis C Patients at Phramongkutklao Hospital
Year2009 NameHiroaki Yanagimoto (Kansai Medical University, Japan) Research TitleThe Beneficial Effect of Active Hexose Correlated Compound (AHCC), a Health Food Component, in Patients with Pancreatic or Biliary Tract Cancer who Underwent Chemotherapy

■ Young Investigator Award

Year Name Research Title
Year2023 NameTetsuro Ishida (Japan Health Care College Hospital, Japan) Research TitleImmunomodulation of functional food AHCC® to prevent COVID-19 central sequelae
Year2022 NameSaki Shirako (Ritsumeikan University, Japan) Research TitleLC-MS/MS analyses of in vitro protease digests of ECLM, EAS, and OPLFE
Year2019 NameJamaluddin Madolangan (Hasanuddin University, Indonesia) Research TitleThe AHCC® effect on clinical outcome of pulmonary tuberculosis in HIV-infected patients
Year2018 NameHonami Oya (Fuji Women’s University, Japan) Research TitleEffects of OligonolR on body weight and body fat reduction: A double-blind, randomized, controlled trial study in healthy adults
Year2017 NameRyo Sakamoto (Ritsumeikan University, Japan) Research TitleEffects of AHCC on the proliferation of human breast cancer cell line, MDA-MB-231
Year2016 NameKensuke Miki (Mima Ladies Clinic, Japan) Research TitleClinical effects of AHCC on high-risk HPV infection and secretory IgA
Year2015 NameKen Shirato (Kyorin University, Japan) Research TitleEnzyme-Treated Asparagus Extract attenuates hydrogen peroxide-induced matrix metalloproteinase-9 expression in murine dermal fibroblast L929
Year2014 NameHideaki Waki (Osaka University, Japan) Research TitleEffect of AHCC on Natural Killer Cells under Psychological Stress
Year2013 NameHayato Urushima (Teikyo Heisei University, Japan) Research TitleThe Efficacy of PerillaExtract on DSS-induced Colitis (the Second Report)
Year2012 NameTempei Miyaji (The University of Tokyo, Japan) Research TitleExploratory Clinical Research on Active Hexose Correlated Compound in the Adjuvant Chemotherapy of Breast Cancer
Year2011 NameHye-Won Yum (Seoul National University, Seoul, Korea) Research TitleProtective Effects of Oligonol on Dextran Sulfate Sodium (DSS)-induced Mouse Colitis and Underlying Biochemical Mechanisms
Year2010 NameTakuya Sakurai (Kyorin University, Japan) Research TitleBoth Oligonol and Exercise Have Preventive Effects on Cognitive Impairment in Senescence-Accelerated Mice
Year2009 NameJudith A. Smith, Pharm.D.(The University of Texas, USA) Research TitleDefining Synergistic Activity of the Combination of Active Hexose Correlated Compound (AHCC) with Liposomal Doxorubicin (Doxil)

■ Best Poster Award

Year Name Research Title
Year2023 NameShigeki Adachi (Osaka University, Japan) Research TitleVerification of antitumor effect of AHCC® combined use in radiotherapy using PDX model
Year2022 NameYusai Kawaguchi (Kitakawachi-Fujii Hospital, Japan) Research TitleInfection status during the hospital cluster outbreak among medical workers who had taken AHCC® as prevention of COVID-19 infection
Year2019 NameKi-Baik Hahm (Seoul National University, South Korea) Research TitleOligonol® to prevent the relapse of ulcerative colitis: Nrf2-mediated antioxidative defense mechanism
Year2018 NameHayato Urushima (Osaka City University, Japan) Research TitleOligonolR suppresses the activation of hepatic stellate cell by inhibition of YAP/TAZ pathway
Year2017 NameRichi Nakatake (Kansai Medical University, Japan) Research TitleAlleviating effect of AHCC on endotoxin-induced liver injury after partial hepatectomy in rats
Year2016 NameNatalia Mikhailichenko (International Medical Center “Nevron”, Russia) Research TitleEvaluation of asparagus extract efficacy in correction of mild andmoderate cognitive disorders in patients with chroniccerebrovascular pathology
Year2015 NameMarie-Francoise Doursout (The University of Texas, USA) Research TitleOral administered AHCC moderates LPS-induced hypotensive response and gut injury in rats
Year2014 NameAlamelu Sundaresan(Texas Southern University, USA) Research TitleAHCC activates human lymphocytes via phenotypic, genotypic and differentiation changes to an adherent cell type. A possible novel mechanism of activation.
Year2013 NameYoshimi Kishimoto(Ochanomizu University, Japan) Research TitleEffects of Oligonol on Lipid Metabolism in HepG2 Cells
Year2012 NameJeong-Beom Lee (Soonchunhyang University, South Korea) Research TitleThe Effect of Oligonol Intake on Leukocytes, T Cell, B Cell, NK Cell, PGE2, COX-2, Orexin, HSP70 and Body Temperature after Heat Stress
Year2011 NameSatoru Yui (Teikyo University, Japan) Research TitleProtective Effect of Oligonol on the Mouse Methyl Nitrosourea-induced Retinitis Pigmentosa Model
Year2010 NameChan Hum Park (University of Toyama, Japan) Research TitleHypolipidemic and Antioxidative Effects of Oligonol Derived from Lychee Fruit on Renal Damage in Type 2 Diabetic Mice
Year2009 NameMiki Sakaue (Osaka University Graduate School of Medicine, Japan) Research TitlePhase I/II Clinical Study of AHCC as Adverse Effect Reducer in Cancer Patients with Chemotherapy (the 3rd Report)

■ Promising Research Award

Year Name Research Title
Year2013 NameGonzalo C. Banuelos Jr. (PROS) Research TitleEffects of Oligonol on Lipid Metabolism in HepG2 Cells

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